How to Convert Estradiol pg/mL to pmol/L
Estradiol (E2) is reported in pg/mL in the US and in pmol/L across most of the world. The conversion factor is 3.671, from estradiol's molecular weight of 272.38 g/mol.
Estradiol pmol/L = estradiol pg/mL × 3.671 Estradiol pg/mL = estradiol pmol/L ÷ 3.671 Estradiol pg/mL to pmol/L Chart
| pg/mL | pmol/L | Typical context |
|---|---|---|
| 15 pg/mL | 55 pmol/L | Postmenopausal / low |
| 30 pg/mL | 110 pmol/L | Early follicular |
| 100 pg/mL | 367 pmol/L | Late follicular |
| 200 pg/mL | 734 pmol/L | Peri-ovulatory |
| 300 pg/mL | 1101 pmol/L | Ovulation range |
| 400 pg/mL | 1468 pmol/L | Ovulation peak |
pmol/L to pg/mL Reverse Chart
| pmol/L | pg/mL |
|---|---|
| 100 pmol/L | 27 pg/mL |
| 367 pmol/L | 100 pg/mL |
| 734 pmol/L | 200 pg/mL |
| 1101 pmol/L | 300 pg/mL |
Estradiol Reference Ranges
Estradiol varies more than almost any other routine hormone, because it tracks the menstrual cycle:
| Group / phase | pg/mL | pmol/L |
|---|---|---|
| Follicular phase | 30–100 pg/mL | 110–367 pmol/L |
| Ovulation (mid-cycle peak) | 100–400 pg/mL | 367–1468 pmol/L |
| Luteal phase | 50–150 pg/mL | 180–550 pmol/L |
| Postmenopausal | Below 30 pg/mL | Below 110 pmol/L |
| Adult men | 10–40 pg/mL | 37–147 pmol/L |
Because of this swing, a single estradiol value only makes sense alongside the cycle day it was drawn. Pregnancy raises estradiol far above these ranges.
Estradiol in Fertility and IVF Monitoring
During ovarian stimulation, clinics track estradiol to judge how follicles are responding — often in pg/mL in the US and pmol/L elsewhere. Because trigger and dose-adjustment thresholds are unit-specific, converting correctly with the 3.671 factor matters when comparing protocols or lab reports across countries.
Worked Example
Suppose a report shows 734 pmol/L and you want pg/mL:
734 ÷ 3.671 = 200 pg/mL 200 pg/mL is a peri-ovulatory level. Converting the other way, a follicular 30 pg/mL is about 110 pmol/L.
Frequently Asked Questions
How do you convert estradiol pg/mL to pmol/L?
Multiply pg/mL by 3.671. For example, 100 pg/mL is about 367 pmol/L.
What is a normal estradiol level?
It depends on cycle phase — roughly 30–400 pg/mL through the cycle, below 30 after menopause, 10–40 in men.
Why does estradiol vary so much?
It rises and falls across the menstrual cycle, peaking before ovulation.
Is estradiol the same as estrogen?
Estradiol (E2) is the main estrogen; estrogen also includes estrone and estriol.
References
- UnitsLab — Estradiol (E2) unit conversion (pg/mL ↔ pmol/L).
- Estradiol factor 3.671 (MW 272.38 g/mol); cycle-phase reference ranges from standard clinical laboratory references.
Conclusion
Converting estradiol between pg/mL and pmol/L is a ×3.671. The result only means something next to the cycle day, menopause status or pregnancy it belongs to — interpret it with your clinician against your lab's ranges.